Italian Penicillin Soup – A Cozy Bowl of Healing Goodness
When I’m feeling under the weather—or even just a little run-down—there’s nothing quite as comforting as a bowl of Italian Penicillin Soup.
Inspired by the healing magic of traditional chicken soup but infused with bold Italian flavors, this hearty bowl of goodness always lifts my spirits.
It’s warm, nourishing, and packed with immune-boosting ingredients that make it the perfect remedy for cold days, sick days, or anytime you need a little extra comfort.
What makes this version truly special is the rich tomato base, tender shredded chicken, garlic, herbs, and a handful of simple Italian staples like pasta or rice, leafy greens, and maybe even a sprinkle of Parmesan.
It’s the kind of meal that tastes like it was made by an Italian grandma—soulful, soothing, and full of love.
Why You’ll Love This Italian Penicillin Soup
🍲 Comforting and healing, like a hug in a bowl
🧄 Packed with garlic, herbs, and veggies to boost your immune system
🇮🇹 Classic Italian flavors that feel cozy and familiar
🍗 Protein-rich with tender shredded chicken
⏱️ Simple to make with pantry-friendly ingredients
Ingredients You’ll Need
- 1 tablespoon olive oil
- 1 small onion, chopped
- 3 cloves garlic, minced
- 2 medium carrots, sliced
- 2 celery stalks, chopped
- 1 (14 oz) can diced tomatoes
- 6 cups chicken broth (preferably homemade or low-sodium)
- 2 cups cooked, shredded chicken (rotisserie works great)
- ½ teaspoon dried oregano
- ½ teaspoon dried basil
- ¼ teaspoon red pepper flakes (optional, for gentle heat)
- Salt and pepper, to taste
- ½ cup ditalini pasta or cooked rice
- 2 cups baby spinach or kale
- Fresh parsley and Parmesan cheese, for garnish
- Optional: juice of ½ lemon for brightness
How to Make Italian Penicillin Soup
🧅 Heat olive oil in a large pot over medium heat. Add onion, carrots, and celery, and sauté for about 5–6 minutes until softened. Stir in the garlic and cook for another 30 seconds.
🍅 Add diced tomatoes, chicken broth, shredded chicken, oregano, basil, red pepper flakes, salt, and pepper. Bring to a boil, then reduce heat and simmer for 15 minutes to let the flavors meld.
🍝 Stir in the pasta (if using uncooked) and cook until tender, about 10 minutes. If using pre-cooked pasta or rice, add it during the last 3–4 minutes just to warm through.
🌿 Add the spinach or kale and stir until wilted, about 2–3 minutes. Squeeze in lemon juice if using—it adds a nice brightness.
🧄 Taste and adjust seasoning as needed. Serve hot, topped with fresh parsley and a sprinkle of Parmesan.
Optional Add-Ins and Variations
🫘 Add a can of cannellini beans for extra fiber and protein
🍋 Stir in lemon zest or more lemon juice for a zesty kick
🥬 Swap spinach with chard, escarole, or any leafy greens
🧀 Stir in a spoonful of ricotta for creamy richness
🍖 Use Italian sausage instead of chicken for a spicier twist
Tips for the Best Italian Penicillin Soup
✔ Use homemade broth if you can—it makes a big difference
✔ Let the soup simmer gently to develop deeper flavor
✔ If making ahead, store pasta separately to avoid over-softening
✔ Add greens at the end so they stay fresh and vibrant
Storage and Reheating
📦 Store in an airtight container in the fridge for up to 4 days
❄️ Freeze without pasta for up to 3 months
🔥 Reheat gently on the stove or in the microwave, adding more broth if needed
Final Thoughts
This Ultimate Italian Penicillin Soup is more than just a recipe—it’s a remedy. It’s what I turn to when I need comfort, nourishment, or just a bowl of something soul-soothing.
Whether you’re feeling a little under the weather or simply craving a taste of Italian home cooking, this soup will take care of you from the first spoonful to the last. Mangia, and feel better soon!
